This is the second time I have this issue, when clicking on a publish application on the Citrix WebInterface I get this weir message : ERROR: The MetaFrame servers reported that the alternate address cannot be found. I mean weird because I'm on a LAN and I don't cross any subnet or different VLAN and there is no alernate address configured on these servers. Error Message at the bottom of my WI :   It looks like the LHC (Local Host Cache) doesn't contain valid informations. And the only way to be sure about that one is to simply recreate the Local Host Cache. So login on the computer and do as follow : Net stop imaservice /y : This command will stop Independant Managment Architecture service, Citrix WMI Service and Citrix SMA Service DSMAINT RECREATELHC Net start imaservice Net start "Citrix WMI Service" Net start "Citrix SMI Service" And this resolve this "small" problem. This is a common Citrix administration task and troubleshoot but if you don't know it, you cannot guess it.